MIDD In Early Oncology Clinical Development: Dose Optimization

Dose optimization has become an increasingly challenging, but necessary task as developers explore more next-generation oncology therapies and novel combinations. Find out how model-informed drug development (MIDD) can play an integral role in keeping vital oncology trials on track to deliver life-saving therapies to patients in need.

Get an inside look at:

• Dose optimization and its challenges in novel modalities
• Addressing dose optimization early in oncologic therapy development
• How to anticipate and address worldwide regulatory hurdles
• Using MIDD to quantitatively evaluate efficacy and safety
• The future of early oncology development

A roadmap to better drug development

Discover the keys to more successful, less risky early drug development with fresh insights into keeping your studies on track and clear of the common mistakes that can add time, expense, and headaches to your projects.

Building Your Early Phase Clinical Data, From Protocol To Regulatory Submission

Learn more about the critical steps toward ensuring the integrity of your clinical trial data for each step of your Phase I clinical trials. Download your free audiobook now.

CNS Drug Development: Integrated Solutions Lessen Complexity

Get an inside look at successfully overcoming common hurdles in central nervous system (CNS) drug development, with your free issue of The Altascientist scientific journal, presented by Citeline in partnership with Altasciences.

Discover new insights into Canada’s benefits

Listen now to “The Advantages of Conducting Early Phase Clinical Research in Canada”, your free audiobook from Citeline, presented in partnership with Altasciences.

Key Biomarkers of Immunomodulation: Complement Factors and Cytokines

Don’t miss these insights in your free copy of “Key Biomarkers of Immunomodulation: Complement Factors and Cytokines” from Citeline, presented in partnership with Altasciences.

Key Considerations As You Move From Discovery to Preclinical to Clinical

Drive your development process forward with insights from “Key Considerations As You Move From Discovery to Preclinical to Clinical” from Citeline, presented in partnership with Altasciences.

A comprehensive approach to improving solubility and bioavailability: Spray drying

Capture essential spray drying insights in your free article from Pharma Ignite, presented in partnership with Thermo Fisher Scientific/Patheon.

Learn more about:

• The role of spray drying in advanced drug development
• How spray drying works
• The importance of a comprehensive approach to spray drying throughout development
• Considerations for scale-up and technology transfer
• The application of analytical and downstream capabilities

Advancing Drug Development Using In Silico Modeling

Download your free report from Pharma Ignite, presented in partnership with Thermo Fisher Scientific/Patheon.

Download now to explore:

• Solubility and bioavailability enhancement in early development
• Stability modeling from preclinical through commercialization
• Formulation and manufacturing process modeling from preclinical through commercialization
• Absorption, distribution, metabolism, excretion, and pharmacokinetics from discovery through commercialization/post-approval

Solving for solubility: A scale-up strategy for spray-dried dispersions

Explore your free case study to learn more about:

• Reduce reduces cost and speeds development of low-solubility compounds
• See how spray dry dispersion offers optimal solubility for the compound while maintaining molecular stability
• See Thermo Fisher’s industry expertise offers a key advantage in overcoming difficult product development challenges.